Job postings

Active job opportunities

 

Exciting post-doc opportunity in Epidemiology / Biostatistics at the Center for Epidemiology Versus Arthritis, Manchester

We are seeking a talented and enthusiastic research associate to work on projects focused on opioid utilization and safety. The successful candidate will take a leading role in the analysis of two research studies utilizing primary and secondary care electronic health records (EHRs) and join a growing team of analysts and methodologists based in the Center for Epidemiology Versus Arthritis (CfE). The CfE is an internationally recognized Center of Excellence for musculoskeletal epidemiology in the UK and a part of the Center for Musculoskeletal Research, a EULAR Center of Excellence.

Based at the CfE, you will work with established primary care EHRs as well as emerging linked secondary and primary care EHRs from a Global Digital Exemplar site. The projects will address a range of research questions in MSK patients to identify patients at high-risk of opioid-related harms. You will gain experience in using a range of platforms using state-of the art statistical methods to address clinically important questions, with potential to drive improvements in future prescribing of opioids and impact policy.

Inquiries about the vacancy, shortlisting and interviews: meghna.jani@manchester.ac.uk and will.dixon@manchester.ac.uk

To apply: https://www.jobs.manchester.ac.uk/displayjob.aspx?jobid=20978

General inquiries:  hrservices@manchester.ac.uk

Technical support: universityofmanchester@helpmeapply.co.uk

Deadline: 14th Oct 2021

 

Rheumatology Clinical Senior Lecturer / Senior Research Fellow

University of Glasgow, United Kingdom

College of Medical, Veterinary & Life Sciences
Research Institute of Infection, Immunity and Inflammation

This is a new Clinical Senior Lecturer/Clinical Senior Research Fellow post in the Centre for Immunobiology at the Institute of Infection, Immunity and Inflammation, University of Glasgow. You will have direct responsibility for developing research programmes bridging the activities and interests of the rheumatology and immunology research community in the Institute and wider College. Rheumatology and Immunology research in the University is focussed in the Centre for Immunobiology and encompasses basic, translational and clinical science. The Centre hosts the EULAR Centre of Excellence in Rheumatology and the Versus Arthritis Research into Inflammatory Arthritis Centre (RACE). Moreover, it engages in a range of strategic industry relationships.

The Institute of Infection, Immunity and Inflammation is part of the College of Medical, Veterinary and Life Sciences. The Institute contains scientists and clinical investigators of global repute and includes geneticists, molecular and cell biologists, biochemists, immunologists, bacteriologists, virologists, parasitologists, pathologists and clinical investigators. This expertise is supported by state of the art basic science technology. The College in turn provides outstanding clinical research facilities and recently opened the Imaging Centre of Excellence that offers superb imaging capacity including 7T MRI on a hospital site.

The successful candidate will be expected to be in possession of a CCT (or equivalent) in Rheumatology. Given the nature of the post the appointee will be expected to have a strong track record in clinical or translational research.

The post is full time and has funding for 4 years in the first instance.

Visit the website below for further information on the University of Glasgow, Research Institute of Infection, Immunity and Inflammation, https://www.gla.ac.uk/researchinstitutes/iii/

Informal Enquires can be directed to Professor Stefan Siebert, Stefan.Siebert@glasgow.ac.uk or Professor James Brewer, James.Brewer@glasgow.ac.uk

Closing Date: 11 October 2021​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​

 

Research Associate in BADBIR, The University of Manchester, UK

An exciting opportunity has arisen on the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR;  www.badbir.org ). BADBIR is a long-term pharmacovigilance register of psoriasis patients receiving biologic or conventional systemic therapies. Established in 2007, BADBIR has 20,000 registrations and is the largest such registry for psoriasis globally.

We are seeking a Research Associate to join the team and help fulfill BADBIR's academic publication plan using a world-leading dataset. The work will include developing an understanding of the data collected, the complex needs of all BADBIR stakeholders and statistical / epidemiological methods to address limitations with the data.

You will assist study staff, students and external stakeholders working on the data. There is significant opportunity to work with academics, NHS partners and pharmaceutical companies in this role. Excellent communication skills are required to effectively tailor and convey information to these groups including lay audiences where required.

A PhD in epidemiology or a related discipline is required. You should have excellent organizational skills and the ability to work well both in a team and using your own initiative. Experience of working with confidential data and experience of using statistical software is essential.

The School is strongly committed to promoting equality and diversity, including the Athena SWAN charter for gender equality in higher education. The School holds a Silver Award which recognizes their good practice in relation to gender; including flexible working arrangements, family-friendly policies, and support to allow staff to achieve a good work-life balance. We particularly welcome applications from women for this post. All appointment will be made on merit. For further information, please visit:  https://www.bmh.manchester.ac.uk/about/equality/

Blended working arrangements may be considered. Please note that we are unable to respond to inquiries, accept CVs or applications from Recruitment Agencies.

Enquiries about the vacancy, shortlisting and interviews contact Prof Chris Griffiths OBE (christopher.griffiths@manchester.ac.uk)

More information: https://www.jobs.manchester.ac.uk/displayjob.aspx?jobid=20377

Closing date: 17th October 2021

 

 

Previous job opportunities

 

PhD Candidate Rheumatology Rheumatoid Arthritis, Leiden, the Netherlands

The position: The Rheumatology department is looking for an ambitious PhD candidate interested in elucidating the immunological mechanisms underlying RA. Do you have affinity / experience with immunological lab techniques and biostatistics, as well as a passion to understand rheumatic diseases? Then we are looking for you!

Background: Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints, in which autoantibodies are often detected. It is however unknown how the break of B cell tolerance is induced or how autoantibody-producing B cells are activated. Although there are strong indications that mucosal immune responses are involved in this process, their exact contribution remains unclear. This is why, in our research group, we have collected biomaterial from mucosal sites and blood from RA patients and healthy individuals. Based on our expertise in characterizing antigen-specific B cells and autoantibodies in RA, this new project will elucidate the role of antigen exposure at mucosal surfaces in the development of the autoimmune response underlying RA. Furthermore, the association between various autoantibody characteristics and clinical parameters will be investigated. Laboratory techniques to be used include B cell staining, both on blood (FACS) and on tissue (immunohistochemistry), enzyme-linked immunosorbent assays (ELISA), techniques to purify antibodies, and possibly work with laboratory animals (mice models). The project involves both fundamental and translational research in a multi-disciplinary and enthusiastic team of technicians, immunologists and rheumatologists.

Your profile: We are looking for a curious and ambitious PhD candidate with an MSc degree in medicine, biomedical or biopharmaceutical sciences or equivalent. You have a flexible mindset, excellent communication skills, and the ability to work in a multidisciplinary team consisting of preclinical scientists, clinicians, and technicians. Affinity with immunology / autoimmune research is appreciated, as well as hands-on experience with bio-statistics and standard immunological techniques such as ELISA and immunohistochemistry.

What we offer: You will be employed on the basis of a 36-hour week. Appointment is for the duration of the education, 4 years. Your salary will depend on your qualifications and experience, with a maximum of € 3,196 gross per month based on a 36-hour week (scale Pro, CAO UMC).

Working at the LUMC: The LUMC, situated in Leiden, the Netherlands, is an academic medical center for patient care, research and education, aiming to meet the challenges of tomorrow’s health care. It has a strong focus on research, connecting and combining fundamental research into disease-causing mechanisms with patient-focused studies in areas like oncology, regenerative medicine and population health. The LUMC has research facilities that include capabilities for multiple appliances. The combination with clinical and societal outreach programs allows for ground-breaking research and innovation in basic and applied science.
At the department of Rheumatology, a EULAR Centre of Excellence, research is performed on the pathogenesis of different autoimmune diseases. The Rheumatology laboratory consists of 35 enthusiastic postdocs, PhD candidates and technicians. The Rheumatology outpatient clinic and the scientists in the lab, work in close collaboration to integrate fundamental and clinical research as much as possible.

More information: A detailed job description can be found at www.lumc.nl / vacancies. Diane van der Woude M.D. Ph.D., rheumatologist, Rheumatology department. Telephone: +31 (0)71 526 34 23, dvanderwoude@lumc.nl

How to apply

Please apply via our online form at

https://lumc.recruitee.com/l/en/o/phd-candidate-reumatology-rheumatoid-arthritis-b21pvel83/c/new

Closing date September 12th 2021

 

Job Opportunity for Clinical Research Associate

Translational and Clinical Research Institute Faculty of Medical Sciences, Newcastle University

The Role

Autologous Tolerogenic Dendritic cells for Rheumatoid Arthritis (AuToDeCRA) is our flagship programme investigating the potential of a cellular therapy, derived from a rheumatoid arthritis patient’s own peripheral blood, to intercept the disease process. We are now preparing for our second human trial of this therapy, AuToDeCRA-2. This study will compare different routes of administration, using immune monitoring to track the impact of this novel cellular therapy over a period of three months. It may also be possible to track the injected cells using MRI. This role is funded by an IMI2 project, Rheumatherapy Cure (RTcure), and linked to a Versus Arthritis project, Autologous Tolerogenic Dendritic Cells for Rheumatoid Arthritis-2 (AuToDeCRA-2). RTcure is studying methods to prevent or cure autoimmune rheumatic diseases, particularly rheumatoid arthritis (RA), with a particular emphasis on biomarkers.

This post provides a unique opportunity for an ambitious clinician to develop a practical understanding of experimental medicine research. The Clinical Research Associate (CRA) will be responsible for delivering AuToDeCRA-2. They will play a central role in the AuToDeCRA-2 team, acting as a liaison between the research laboratory team, the Good Manufacturing Practice (GMP) advanced therapies laboratory, the NHS rheumatology team and the NIHR Clinical Research Facility. The postholder will be responsible for identifying potential participants, via face-to-face and telephone consultations, explaining the study to them, and obtaining consent. They will also be responsible for overall trial management and logistics, including oversight of study visits, preparing study reports and manuscripts. We have a well-staffed laboratory infrastructure and there may also be the possibility to develop laboratory skills, dependent on further funding.

You are a dynamic, conscientious, self-motivated team player, with a thirst for new knowledge and an appetite for discovery. This post is funded for two years but will provide an excellent platform for a research fellowship, potentially leading to a higher degree. You will work closely with various members of the Musculoskeletal Research Group, particularly Professor J Isaacs and Dr A Pratt, to whom informal enquiries can be made: john.isaacs@ncl.ac.uk, Arthur.pratt@ncl.ac.uk

Candidates should attach a statement to their application that describes their research interests and, in particular, highlights their relevant experience.

Deadline: 31st July 2021

For more information and to apply, visit:

https://jobs.ncl.ac.uk/job/Newcastle-Clinical-Research-Associate/675318601/

 

Main Dutues and Responsibilities

  • Familiarise oneself with study protocol and all other relevant study documentation.
  • Develop a logistical framework for participants, to enable efficient participation – in particular arranging for imaging investigations if relevant, and liaison between the advanced therapies facility, musculoskeletal research laboratories, clinical research facility and trial team.
  • Learn to perform intradermal injections (if not already skilled in this procedure).
  • Develop a standard operating procedure for handling of research blood samples after acquisition.
  • Identify suitable participants for AuToDeCRA-2 and, where appropriate, obtain informed consent.
  • Oversee study participation, including cell injection.
  • Ensure that, once collected, research samples are processed and stored appropriately, according to the standard operating procedure.
  • Alongside other AuToDeCRA-2 investigators, devise an appropriate data analysis plan for the study.
  • Develop study reports and prepare data for publication in relevant, high impact factor journals.
  • Provide guidance to other staff and students, potentially including supervision of undergraduate research project students.
  • Attend and present your work at laboratory, and national/international meetings.
  • Be prepared to contribute to events celebrating the public engagement of science/social sciences/humanities.

 

Key Accountabilities

  • Contribution to the research programme of the Translational and Clinical Research Institute under the clear guidance of a member of an academic staff or Principal Investigator.
  • Co-ordinate own work with that of others, deal with problems which may affect the achievement of research objectives and contribute to the planning of the project
  • Present information on research progress and outcomes to the Principal Investigator or groups overseeing the research project
  • Write up results from own research activity and provide input into the research project’s dissemination, in whatever form (report, papers, chapters)
  • Work to deadlines and manage, with support, competing priorities
  • Ensure that personal knowledge and training in relevant fields of study is kept up to date
  • Closely managed by a senior academic or Principal Investigator
  • May work with other researchers in a team and actively participate in collaborative research
  • Liaise with research colleagues and support staff on day-to-day issues
  • May provide guidance as required to any support staff and/or research students
  • May in some parts of the University work alongside, and help informally, students working in the same laboratory
  • May be involved in the recruitment and delivery of other related clinical trials and support the specialist clinical rheumatology services.

 

Knowledge, Skills and Experience

Essential

  • Considerable subject knowledge in rheumatology and autoimmune rheumatic disease
  • The ability to work flexibly according to study needs
  • The ability to work collaboratively with colleagues
  • Good level of analytical skills and the ability to communicate complex information clearly, both orally and through the written word.
  • The ability to use personal initiative and creativity to solve research problems
  • Ability to extract and interpret complex medical information from medical records
  • Interpersonal skills to communicate effectively with patients and families
  • Excellent planning and organization skills and ability to prioritize competing demands
  • Excellent record keeping

Desirable

  • Demonstrable clinical research experience in rheumatology and autoimmune rheumatic disease, particularly rheumatoid arthritis
  • Training in GCP and taking informed consent
  • Evidence of academic aptitude (eg publications / presentations)
  • Experience of using electronic patient records
  • Experience in the recruitment, conduct and care of patients participating in experimental medicine studies

Attributes and Behavior

  • Able to work as part of a team but also independently
  • Able to collect, organize and analyze complex datasets
  • Conscientious
  • Enthusiastic and curious
  • Ability to work flexibly, and under pressure
  • Good interpersonal skills; able to effectively work with others, including colleagues, other staff, patients and their families

 

Qualifications

  • Degree in medicine
  • GMC registration
  • MRCP part 1 UK or equivalent