What Is New - Osteoarthritis
Take a look at our 'What is new' highlights in osteoarthritis!
May 2023
"Assessing the importance of predictors of adherence to a digital self‑management intervention for osteoarthritis"
Why WIN?
Digital self-management interventions are becoming increasingly popular in the management of osteoarthritis (OA) due to their portability, flexibility, and acceptability. Greater treatment adherence has been shown to be associated with improved outcomes in people with OA. Therefore, identifying the factors that can improve adherence to digital interventions is crucial for enhancing their effectiveness.
Are you aware of some factors that can improve adherence to OA first-line interventions?
Yes / No
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Link to original article: https://josr-online.biomedcentral.com/articles/10.1186/s13018-023-03562-6
April 2023
"Effects of Running on the Development of Knee Osteoarthritis An Updated Systematic Review at Short-Term Follow-up"
Why WIN?
The belief that land-based physical activity can impact the development of knee osteoarthritis is still common as laypeople and clinicians keep seeing OA as a “wear-and-tear” disease. Conversely, more and more evidence supports the beneficial effects of land-based physical activity (e.g., running) and exercises on the general joint wealth.
Did you know physical activity can be beneficial rather than harmful in OA management?
Yes / No
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March 2023
"Interventions for osteoarthritis pain: A systematic review with network meta-analysis of existing Cochrane reviews"
Why WINS?
It is essential to gather more evidence on the efficacy of treatments for osteoarthritis pain. Hence, studies that pool data from primary studies are necessary. In this regard, this network meta-analysis was conducted, gathering data from 445 RCTs that assessed the impact of various interventions on osteoarthritis pain.
What factors can enhance the quality of evidence on osteoarthritis interventions?
- More attention in choosing the population (eg, identifying different phenotypes)
- More attention in choosing the appropriate comparison
- More attention in designing the RCTs
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February 2023
" Potential effects of teriparatide (PTH (1-34)) on osteoarthritis: a systematic review "
Why WINS?
Teriparatide could be a possible disease-modifying OA drug through the drug repurposing process.
Interactive question
Could you give some other examples of drug repurposing in rheumatology? yes/no
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Jan 2023
" A systematic review of the sex differences in risk factors for knee osteoarthritis "
Why WINS?
This review presents the first high-quality evidence regarding gender differences and risk for osteoarthritis development
Interactive question
Is a gender-targeted approach to OA prevention required in routine clinical practice? yes/no
Join the discussion on twitter... Share your response with us using the hashtag #EMEUNETwhatisnew and tag us @EMEUNET
December 2022
" Risk Assessment for Hip and Knee Osteoarthritis Using Polygenic Risk Scores "
Why WINS?
Polygenic risk scores (PRS) have been utilized as a tool to stratify individuals into different risk groups and they are currently explored for several diseases
Interactive question
Can polygenic risk scores be useful in OA prevention in the near future? yes/ no
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October 2022
" Whole grain consumption and risk of radiographic knee osteoarthritis: a prospective study from the Osteoarthritis Initiative "
Why WINS?
There is strong evidence that nutritional regimens for weight loss are effective treatment for knee osteoarthritis (KOA). A diet rich in whole grains might be further beneficial for preventing KOA in susceptible people
Interactive question
Do you recommend specific diet regimens for patients with knee osteoarthritis? If yes, feel free to share your expertise? Yes/No
Join the discussion on twitter... Share your response with us using the hashtag #EMEUNETwhatisnew and tag us @EMEUNET
September 2022
"Serum biomarkers in prednisolone treated hand osteoarthritis patients"
Why WIN?
Hand osteoarthritis is a highly prevalent condition causing disability that has largely been ignored. This study analyzed biomarkers modulated by prednisolone treatment in patients with hand OA. Their ability to predict response to prednisolone was also assessed.
Interactive question
Do you use systemic prednisolone in the management of hand osteoarthritis?
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May 2022
"Osteoarthritis endotype discovery via clustering of biochemical marker data"
Why WINS?
This study identified three endotypes associated with three distinct osteoarthritis phenotypes based on a large set of biomarkers in a cohort of patients with tibiofemoral osteoarthritis.
Interactive question
Do you believe that patient stratification using biomarkers is a useful strategy for future clinical trials aiming at identifying effective treatments for patients with osteoarthritis?
yes/no
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November 2021
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December 2018
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Sep 2018
Click here to be directed to the article by Gao et al (2018).
Aug 2018
Click here to be directed to the article by Zhang et al (2018).
July 2018
Click here to be directed to the article by Yalong et al (2018).
Click here to be directed to the article by Tang et al (2018).
June 2018
Click here to be directed to the article by Tofiño-Vian et al (2018).
May 2018
Click here to be directed to the article by Soul et al (2018).